4/22/2024 – Congratulations to Pete, Adrian, and Jennifer on passing their 2nd year Thesis Background Exam!
2/8/2024 – Congratulations to Minji, Karina, Dylan, and Diana on their mini-review article demonstrating the use of alkene thianthrenation to access diverse cation synthons!
Oxidative alkene functionalization reactions are a fundamental class of complexity-building organic transformations. However, the majority of established approaches rely on electrophilic reagents that limit the diversity of groups that can be installed. Recent advances have …
12/13/2023 – Congratulations to Karina for successfully defending her dissertation and becoming Dr. Targos!
12/1/2023 – Welcome Liza to our team as a graduate student! We’re so excited to have you!
7/9/2023 – Congratulations to Joe, Sara, Nick, and Jennifer on developing an electrophotocatalytic approach to enable intermolecular ketyl radical coupling!
Herein, we report a new class of electrophotocatalysts, polycyclic aromatic hydrocarbons, that promote the reduction of unactivated carbonyl compounds to generate versatile ketyl radical intermediates. This catalytic platform enables previously challenging intermolecular ketyl radical coupling …
5/15/2023 – Congratulations to Sara, Jimin, Y, and Camille on developing a new catalytic system that unlocks hydrocarboxylation for unactivated alkenes!
Herein we disclose a strategy to promote the hydrocarboxylation of unactivated alkenes using photochemical activation of formate salts. We illustrate that an alternative initiation mechanism circumvents the limitations of prior approaches and enables hydrocarboxylation of …
5/15/2023 – Congratulations to Jimin, Y, and Uriel on passing the 2nd year Thesis Background Exam!
4/21/2023 – Congratulations to Dylan for successfully defending his dissertation and becoming Dr. Holst!
4/6/2023 – Congratulations to Dylan, Céline, Casey, and Ilia on developing a new platform for alkene aminofunctionalization!
Modular strategies to rapidly increase molecular complexity have proven immensely synthetically valuable. In principle, transformation of an alkene into a dielectrophile presents an opportunity to deliver two unique nucleophiles across an alkene. Unfortunately, the selectivity …