12/23/2022 – Congratulations to Myriam and Sara on their work on heteroarene hydrocarboxylation reaction that translates 2D heterocycles into versatile 3D analogs. Out on the rxiv now!

The rapid preparation of complex three-dimensional (3D) heterocyclic scaffolds is a key challenge in modern medicinal chemistry. Small molecule therapeutic candidates with increased 3D complexity, on average, possess a higher probability of clinical success. However, …