Herein, we introduce a new synthetic protocol for azole alkylation. Our strategy first engages azoles using alkenylthianthrenium electrophiles to provide 1,2-azolothianthrenium salts, then selectively excises the sulfonium moiety via single electron transfer (SET). Given that …
07/15/2026- Congrats to Joe, Arindam, Niket, Matt and Alissia for their report of selectivity arising from indiscriminate photoreduction!
Single electron transfer (SET) reduction is amongst the most fundamental strategies for the activation of organic compounds. The design of selective reactions that leverage SET is grounded by the premise that differences in substrate redox …
07/01/2026- Congrats to Uriel for defending his thesis!
06/29/2026- Congrats to Jimin for defending her thesis!
05/06/2026 – Congrats to Joe for defending his thesis!
05/05/2026 – Congrats to Matt, Erin, Adam and Caitlin on passing the 2nd year Thesis Background Exam!
12/20/2025 – Congrats to Liza on passing the 3rd year Reserach Proposal Exam!
11/30/2025 – Our first-years are here! Welcome Ben, Bresy, and Stefanie to the group!
11/1/2025 – Welcome our new Postdoc – Alex to the group! We’re so excited to have you here!
9/18/2025 – Congratulations to Pete, Liza, Poulami, Remy, Karina, Tetsuya, Megan for their development of a Z-selective C-H functionalization approach via a stereo-reverse E2 mechanism!
The stereoselective functionalization of C–H bonds represents a central challenge in modern organic synthesis. Despite decades of innovation in C–H activation chemistry, methods for Z-selective functionalization of alkenes have eluded synthetic practitioners. Terminal alkenes present the …