9/18/2025 – Congratulations to Pete, Liza, Poulami, Remy, Karina, Tetsuya, Megan for their development of a Z-selective C-H functionalization approach via a stereo-reverse E2 mechanism!

The stereoselective functionalization of C–H bonds represents a central challenge in modern organic synthesis. Despite decades of innovation in C–H activation chemistry, methods for Z-selective functionalization of alkenes have eluded synthetic practitioners. Terminal alkenes present the …