Year: 2025
11/1/2025 – Welcome our new Postdoc – Alex to the group! We’re so excited to have you here!
9/18/2025 – Congratulations to Pete, Liza, Poulami, Remy, Karina, Tetsuya, Megan for their development of a Z-selective C-H functionalization approach via a stereo-reverse E2 mechanism!
The stereoselective functionalization of C–H bonds represents a central challenge in modern organic synthesis. Despite decades of innovation in C–H activation chemistry, methods for Z-selective functionalization of alkenes have eluded synthetic practitioners. Terminal alkenes present the …
8/26/2025 – Congratulations to Céline, Adrian, Karina, Sara, Dylan, Tom, and our collaborators at Janssen for their development of an N-regioselective alkylation method for azoles using alkenyl thianthreinum salts!
Azoles are important synthetic targets due to their diverse applications in areas ranging from human health to food security. Accordingly, access to N-functionalized azoles is an essential goal in modern synthetic chemistry. Surprisingly, however, the relied-upon …