Azoles are important synthetic targets due to their diverse applications in areas ranging from human health to food security. Accordingly, access to N-functionalized azoles is an essential goal in modern synthetic chemistry. Surprisingly, however, the relied-upon …
8/1/2025 – Welcome Anthony to our group for his Postdoc fellowship! We’re so excited to have you!
4/21/2025 – Congratulations to Minji for successfully defensing her thesis and becoming Dr. Kim!
2/14/2025 – Congratulations to Sara for successfully defending her thesis and becoming Dr. Alektiar!
12/12/2024 – Congratulations to Y, Jimin, Alyah, Sara, and Myriam on their development of a new alkene carboxy-alkylation with formate-derived CO2•–!
Herein, we introduce a new platform for alkene carboxy-alkylation. This reaction is designed around CO2•– addition to alkenes followed by radical polar crossover, which enables alkylation through carbanion attack on carbonyl electrophiles. We discovered that CO2•– adds …
11/21/2024 – Welcome Adam, Caitlin, Erin, and Matt as first-year graduate students to the group! We’re so excited to have you all!
9/20/2024 – A big welcome to our visiting graduate students – Alissia, Jiwoo, and Jiin – as well as our undergraduate researcher, Andrew! Excited to have y’all!
6/1/2024 – Welcome Mina, Bresy, Ari, Jack, and Nhi as our summer undergraduate researchers to the group! We’re so excited to have you!
5/20/2024 – Congratulations to Alyah for successfully defending her dissertation and becoming Dr. Chmiel!
Reductive single electron transfer (SET) to small molecules is a fundamental elementary step that underpins diverse and powerful synthetic transformations. The exquisite chemoselectivity of photoredox catalysis has rendered it an attractive strategy for promoting reductive …
5/13/2024 – Congratulations to Karina and Minji as well as our collaborators from the Gutierrez group (Achyut and Ángel) on the disclosure of the mechanism for Z-selective allylic functionalization from Thianthrenium salts!
A detailed mechanistic study of the Z-selective allylic functionalization via thianthrenium salts is presented. Kinetic analyses, deuterium labeling experiments, and computational methods are used to rationalize the observed reactivity and selectivity. We find that the reaction …