Year: 2021
12/8/2021 – A big welcome to our new 1st year graduate students, Jimin, Uriel, and Y! Excited to have y’all!
11/9/2021 – Congratulations to Diana and Karina on their work coupling alkenes and amines to form (Z)-allylic amines. Out on the rxiv now!
Allylic amines are valuable synthetic targets en route to diverse biologically active amine products. Current allylic C–H amination strategies remain limited with respect to the viable N-substituents. Herein we disclose a new electrochemical process to …
7/22/2021 – Congratulations to Sara on her work splitting formate into H• and CO2•– to hydrocarboxylate alkenes. Out on the rxiv now!
Herein we disclose a new photochemical process to prepare carboxylic acids from formate salts and alkenes. This redox-neutral hydrocarboxylation proceeds in high yields across diverse functionalized alkene substrates with excellent regioselectivity. This operationally simple procedure …
6/30/2021 – Welcome Dora Aranda to the group as an undergraduate researcher!
6/22/2021 – Congratulations to Dylan, Diana, and Minji on their work on aziridine synthesis through coupling unactivated alkenes and primary amines via metastable dicationic intermediates. Out in Nature now!
Aziridines, three-membered nitrogen-containing cyclic molecules, are important synthetic targets. Their significant ring strain and resultant proclivity towards ring opening reactions makes them versatile precursors to diverse amine products and, in some cases, the aziridine functional group itself imbues important …
6/10/2021 – Congratulations to Alyah, Oliver, and Colleen on their work exploiting non-innocent radical anion intermediates in photoredox catalysis for promoting diverse coupling reactions of classically inert aryl chlorides. Out on JACS now!
We describe a photocatalytic system that elicits potent photoreductant activity from conventional photocatalysts by leveraging radical anion intermediates generated in situ. The combination of isophthalonitrile and sodium formate promotes diverse aryl radical coupling reactions from abundant …
6/7/2021 – Welcome Madeleine Robinson to the group as an undergraduate researcher!
6/2/2021 – Congratulations to Colleen and Alyah on their work expanding the pool of photoactive radical anions by electron-priming conventional photocatalysts. Out on ACIE now!
Herein, we leverage electrochemistry to examine the photocatalytic activity of a range of structurally diverse persistent radical anions and find that many are effective electrophotocatalysts. These studies uncover a new electron-primed photoredox catalyst capable of …